Novartis' Focetria and GlaxoSmithKline's Pandemrix vaccines both use adjuvants, chemical compounds used to boost the immune system and stretch the vaccine's active ingredient. The adjuvant used by Novartis has been used in flu vaccines since 1997 in more than 45 million doses, while GlaxoSmithKline's adjuvant has only been tested in clinical trials involving several thousand people.
The European Medicines Agency also said pregnant women and children older than six months should get two doses. There is limited information on how safe vaccines with adjuvants are in both these groups, thought to be particularly vulnerable in a pandemic. Some countries, such as Canada, are buying vaccines without adjuvants for pregnant women.
Via AP
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